{"id":4153,"date":"2026-08-19T10:56:49","date_gmt":"2026-08-19T10:56:49","guid":{"rendered":"https:\/\/www.concyl.es\/?page_id=4153"},"modified":"2026-08-19T10:56:50","modified_gmt":"2026-08-19T10:56:50","slug":"azafran","status":"publish","type":"page","link":"https:\/\/www.concyl.es\/index.php\/azafran\/","title":{"rendered":"Azafr\u00e1n"},"content":{"rendered":"<style>\n        \/* Estilos generales *\/\n        body {\n            font-family: Arial, sans-serif;\n            margin: 0;\n            padding: 0;\n            background-color: #f4f4f4;\n        }\n\n        \/* Contenedor principal *\/\n        .contenedor {\n            max-width: 759px;\n            margin: 0 auto;\n            padding: 0 10px;\n            background-color: #fff;\n            box-shadow: 0 0 10px rgba(0,0,0,0.1);\n        }\n\n        .separator {\n            margin: 20px 0 0 0 !important;\n            text-align: center;\n            color: #FFFCD1 !important;\n            background: #006938 !important;\n            width: 100%;\n            box-sizing: border-box;\n            \/*padding: 10px 0;*\/\n            font-size: 1.5em;\n            font-weight: bold; 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  \n            font-weight: bold !important;\n            line-height: 1.3 !important;\n        }\n\n        .texto-columna p,\n        .texto-columna ul,\n        .texto-columna ol,\n        .texto-columna hr {\n            margin: 15px 0;\n            text-align: justify;\n            line-height: 1.6;\n        }\n\n        .texto-columna ul {\n            list-style-type: disc;\n            padding-left: 20px;\n        }\n\n        .texto-columna ol {\n            padding-left: 30px;\n        }\n\n        .texto-columna hr {\n            border: 0;\n            height: 1px;\n            background: #ccc;\n        }\n\n        .enlaces-titulo {\n            margin-top: 20px !important;\n        }\n\n        .lista-enlaces {\n            list-style-type: none !important;\n            padding-left: 0 !important;\n        }\n\n        .lista-enlaces li {\n            color: #006938 !important;\n            font-weight: bold !important;\n        }\n\n        .lista-enlaces a {\n            text-decoration: none !important;\n            color: #006938 !important;\n            font-weight: bold !important;\n        }\n\n        .lista-enlaces a:hover {\n            text-decoration: underline !important;\n        }\n<\/style> \n\n<div class=\"contenedor\">\n<h1 class=\"separator\">AZAFR\u00c1N (Crocus sativus L.)<\/h1>\n\n<div class=\"image-grid\">\n<div class=\"image-grid-item\"><img decoding=\"async\" class=\"clickable-image\" src=\"https:\/\/www.concyl.es\/wp-content\/uploads\/2026\/08\/Diapositiva1.jpg\" alt=\"Diapositiva 1\" \/><\/div>\n<div class=\"image-grid-item\"><img decoding=\"async\" class=\"clickable-image\" src=\"https:\/\/www.concyl.es\/wp-content\/uploads\/2026\/08\/Diapositiva2.jpg\" alt=\"Diapositiva 2\" \/><\/div>\n<div class=\"image-grid-item\"><img decoding=\"async\" class=\"clickable-image\" src=\"https:\/\/www.concyl.es\/wp-content\/uploads\/2026\/08\/Diapositiva3.jpg\" alt=\"Diapositiva 3\" \/><\/div>\n<div class=\"image-grid-item\"><img decoding=\"async\" class=\"clickable-image\" src=\"https:\/\/www.concyl.es\/wp-content\/uploads\/2026\/08\/Diapositiva4.jpg\" alt=\"Diapositiva 4\" \/><\/div>\n<div class=\"image-grid-item\"><img decoding=\"async\" class=\"clickable-image\" src=\"https:\/\/www.concyl.es\/wp-content\/uploads\/2026\/08\/Diapositiva5.jpg\" alt=\"Diapositiva 5\" \/><\/div>\n<\/div>\n<\/div>\n\n<div class=\"contenedor\">\n<div class=\"texto-columna\">\n\n<p>El azafr\u00e1n (<em>Crocus sativus<\/em> L.) es una especia obtenida de los estigmas secos de una planta perteneciente a la familia Iridaceae. Adem\u00e1s de su uso culinario, en los \u00faltimos a\u00f1os ha despertado un gran inter\u00e9s cient\u00edfico por sus posibles beneficios sobre la salud. Sus principales compuestos bioactivos son las <strong>crocinas<\/strong>, la <strong>crocetina<\/strong>, la <strong>picrocrocina<\/strong> y el <strong>safranal<\/strong>, responsables de su actividad <strong>antioxidante<\/strong> y de sus <strong>efectos sobre el SNC.<\/strong><\/p>\n\n<p>El azafr\u00e1n no es un nutriente esencial, por lo que <strong>no existe una Ingesta Diaria Recomendada (IDR).<\/strong> El organismo humano no sintetiza sus principios activos, por lo que su aporte es exclusivamente <strong>ex\u00f3geno<\/strong>, ya sea mediante su uso culinario o a trav\u00e9s de complementos alimenticios.<\/p>\n\n<p>La evidencia cient\u00edfica actual atribuye al azafr\u00e1n una <strong>acci\u00f3n antioxidante y antiinflamatoria<\/strong>, adem\u00e1s de un posible efecto modulador sobre neurotransmisores como la serotonina, la dopamina y la noradrenalina. Estos mecanismos podr\u00edan explicar los beneficios observados en algunos estudios sobre el estado de \u00e1nimo y la funci\u00f3n cognitiva.<\/p>\n\n<p>Actualmente, la indicaci\u00f3n con mayor respaldo cient\u00edfico es su utilizaci\u00f3n como <strong>complemento en personas con s\u00edntomas leves o moderados de ansiedad y depresi\u00f3n<\/strong>, siempre bajo supervisi\u00f3n de un profesional sanitario y sin sustituir los tratamientos prescritos. Tambi\u00e9n existe evidencia prometedora sobre su utilidad en el s\u00edndrome premenstrual, el bienestar emocional y determinadas funciones cognitivas, aunque son necesarios m\u00e1s estudios para confirmar estos efectos.<\/p>\n\n<p>La mayor parte de los ensayos cl\u00ednicos emplean <strong>extractos estandarizados de <em>Crocus sativus<\/em><\/strong> administrados por <strong>v\u00eda oral<\/strong>, principalmente en forma de <strong>c\u00e1psulas<\/strong>. La dosis m\u00e1s estudiada es de <strong>30 mg diarios<\/strong> (15 mg cada 12 horas o 30 mg en una \u00fanica toma), durante periodos de <strong>6 a 12 semanas.<\/strong><\/p>\n\n<p>El azafr\u00e1n presenta un buen perfil de seguridad cuando se utiliza en las dosis recomendadas. No obstante, <strong>no se aconseja durante el embarazo ni la lactancia<\/strong> por la escasez de datos de seguridad. Asimismo, se recomienda precauci\u00f3n en personas con trastornos hemorr\u00e1gicos, hipotensi\u00f3n arterial o en tratamiento con anticoagulantes, antiagregantes, antihipertensivos o antidepresivos, debido a posibles interacciones farmacol\u00f3gicas.<\/p>\n\n<p>Desde la pr\u00e1ctica farmac\u00e9utica, el azafr\u00e1n puede considerarse un complemento alimenticio \u00fatil en personas con s\u00edntomas leves de ansiedad, bajo estado de \u00e1nimo o s\u00edndrome premenstrual, siempre tras una adecuada valoraci\u00f3n individual y utilizando productos de calidad con extractos estandarizados.<\/p>\n\n<h3 class=\"titulo-seccion\">Bibliograf\u00eda<\/h3>\n\n<ol>\n<li>Marx W, Lane M, Rocks T, Ruusunen A, Loughman A, Lopresti AL, et al. Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis. Nutr Rev. 2019;77(8):557-571.<\/li>\n\n<li>Lopresti AL, Drummond PD. Saffron (<em>Crocus sativus<\/em>) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action. Hum Psychopharmacol. 2014;29(6):517-527.<\/li>\n\n<li>Hausenblas HA, Saha D, Dubyak PJ, Anton SD. Saffron (<em>Crocus sativus<\/em> L.) and major depressive disorder: a meta-analysis of randomized clinical trials. J Integr Med. 2013;11(6):377-383.<\/li>\n\n<li>Yang X, Chen X, Fu Y, Luo Q, Du L, Qiu H, et al. Comparative efficacy and safety of <em>Crocus sativus<\/em> L. for treating mild to moderate major depressive disorder in adults: a meta-analysis of randomized controlled trials. Neuropsychiatr Dis Treat. 2018;14:1297-1305.<\/li>\n\n<li>Khaksarian M, Behzadifar M, Behzadifar M, Alipour M, Jahanpanah F, Re TS, et al. The efficacy of <em>Crocus sativus<\/em> (Saffron) versus placebo and fluoxetine in treating depression: a systematic review and meta-analysis. Psychol Res Behav Manag. 2019;12:297-305.<\/li>\n\n<li>Melnyk JP, Wang S, Marcone MF. Chemical and biological properties of the world's most expensive spice: saffron. Food Res Int. 2010;43(8):1981-1989.<\/li>\n\n<li>Cardone L, Castronuovo D, Perniola M, Cicco N, Candido V. Saffron (<em>Crocus sativus<\/em> L.), the king of spices: an overview. Sci Hortic. 2020;272:109560.<\/li>\n\n<li>Pitsikas N. The effects of <em>Crocus sativus<\/em> L. and its constituents on memory: basic studies and clinical applications. Evid Based Complement Alternat Med. 2015;2015:926284.<\/li>\n<\/ol>\n\n<h3 class=\"separator enlaces-titulo\">Enlaces<\/h3>\n\n<ul class=\"lista-enlaces\">\n<li><a href=\"https:\/\/www.linkedin.com\/posts\/concyl-consejo-de-colegios-profesionales-de-farmac%C3%A9uticos-42b03034a_el-azafr%C3%A1n-no-es-solo-para-la-paella-la-ugcPost-7495746490620010496-05AW\/?utm_source=share&amp;utm_medium=member_android&amp;rcm=ACoAAFc2lWMBZTV6T2CbdBqIY8hJo0SdZgPTrgs\" target=\"_blank\" rel=\"noopener\">Enlace a LinkedIn<\/a><\/li>\n\n<li><a href=\"https:\/\/x.com\/FarmaConcyl\/status\/2089978911434199108\" target=\"_blank\" rel=\"noopener\">Enlace a X<\/a><\/li>\n\n<li><a href=\"https:\/\/www.instagram.com\/p\/DcNsLlhiKvY\/?igsh=YzB0YzBsaGNydzB4\" target=\"_blank\" rel=\"noopener\">Enlace a Instagram<\/a><\/li>\n<\/ul>\n\n<\/div>\n<\/div>\n\n<div id=\"imageModal\" class=\"modal\">\n    <span class=\"close-modal\">\u00d7<\/span>\n    <img id=\"modalImage\" class=\"modal-content\" \/>\n<\/div>\n\n<script>\n    const modal = document.getElementById('imageModal');\n    const modalImg = document.getElementById('modalImage');\n    const closeModal = document.getElementsByClassName('close-modal')[0];\n    const images = document.querySelectorAll('.clickable-image');\n\n    images.forEach(img => {\n        img.addEventListener('click', () => {\n            modal.style.display = 'block';\n            modalImg.src = img.src;\n            modalImg.alt = img.alt;\n        });\n    });\n\n    closeModal.addEventListener('click', () => {\n        modal.style.display = 'none';\n    });\n\n    window.addEventListener('click', (e) => {\n        if (e.target === modal) {\n            modal.style.display = 'none';\n        }\n    });\n\n    document.addEventListener('keydown', (e) => {\n        if (e.key === \"Escape\" && modal.style.display === 'block') {\n            modal.style.display = 'none';\n        }\n    });\n<\/script>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-full-width.php","meta":{"footnotes":""},"class_list":["post-4153","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/pages\/4153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/comments?post=4153"}],"version-history":[{"count":1,"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/pages\/4153\/revisions"}],"predecessor-version":[{"id":4154,"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/pages\/4153\/revisions\/4154"}],"wp:attachment":[{"href":"https:\/\/www.concyl.es\/index.php\/wp-json\/wp\/v2\/media?parent=4153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}